Biotech Stocks Under $5 - Hot Biotech Penny Stocks

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Biotech Penny Stocks

Biotech Stocks Under $5 is a list of the top pharmaceutical penny stocks trading on NYSE, NASDAQ, and AMEX. These biotech and pharmaceutical penny stocks are trading under $5 per share and sorted by the biggest gain of the day.

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published on May 23, 2025

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Symbol

Company

Open

High

Low

Volume

Percent

TLSA

Tiziana Life Sciences Plc ADR

1.44

1.68

1.42

1.58

867K

15.33%

GNPX

Genprex Inc

0.27

0.28

0.26

0.28

629K

7.69%

SLS

Seligman Lasalle Intl Real Est Fund Inc

1.77

1.93

1.74

1.89

7.39%

ONCY

Oncolytics Biotech, Inc

0.40

0.44

0.37

0.42

5.00%

CTMX

Cytomx Thera

2.06

2.29

2.03

2.23

4.69%

YMAB

Y-Mabs Therapeutics Inc

4.01

4.33

4.00

4.32

234K

4.60%

ADAP

Adaptimmune Ther Ads

0.27

0.29

0.26

0.28

386K

3.70%

MBOT

Microbot Medical Inc

2.50

2.67

2.47

2.66

3.50%

GOSS

Gossamer Bio Inc

1.12

1.21

1.12

1.20

3.45%

PRPH

ProPhase Labs Inc

0.30

0.34

0.30

0.32

874K

3.23%

HBIO

Harvard Bioscience, Inc

0.32

0.34

0.32

0.34

372K

3.03%

FBIO

Fortress Biotech Inc

1.73

1.78

1.69

1.78

145K

2.89%

URGN

Urogen Pharma Ltd

3.92

4.23

3.71

4.19

2.70%

AQST

Aquestive Therapeutics Inc

2.25

2.38

2.22

2.35

2.62%

ACHV

Achieve Life Sciences Inc

2.90

3.05

2.89

3.04

112K

2.36%

STRO

Sutro Biopharma Inc

0.87

0.92

0.85

0.92

721K

2.22%

VNDA

Vanda Pharmaceuticals Inc

4.20

4.33

4.17

4.33

297K

2.12%

VERU

Veru Inc

0.49

0.50

0.48

0.50

948K

2.04%

IOVA

Iovance Biotherapeutics Inc

1.70

1.79

1.67

1.78

1.71%

IFRX

Fireman B.V.

1.78

1.90

1.75

1.85

212K

1.65%

BTAI

Bioxcel Therapeutics Inc

1.36

1.42

1.30

1.39

105K

1.46%

AKBA

Akebia Therapeutics

2.81

2.87

2.76

2.86

1.06%

MBRX

Metabasis Therapeutics, Inc

0.94

0.96

0.92

0.95

104K

1.06%

AGEN

Antigenics, Inc

3.70

3.84

3.59

3.82

423K

0.79%

AUTL

Autolus Therapeutics Plc ADR

1.53

1.54

1.49

1.54

0.65%

CRVS

Corvus Pharma Com

3.46

3.51

3.38

3.49

465K

0.58%

CKPT

Checkpoint Therapeutics Inc

4.17

4.19

4.16

4.19

0.48%

QTRX

Quanterix Corp

4.64

4.89

4.60

4.85

410K

0.41%

ARDX

Ardelyx Inc

3.86

4.00

3.86

3.97

0.25%

AEMD

Aethlon Medical

0.39

0.40

0.38

0.40

160K

0.00%

CLRB

Cellectar Biosc

0.25

0.26

0.24

0.25

345K

0.00%

ITRM

Iterum Therapeutics Plc

0.92

0.94

0.91

0.93

375K

0.00%

OVID

Ovid Therapeutics Inc

0.29

0.28

0.29

519K

0.00%

FGEN

Fibrogen Inc CS

0.34

0.32

0.33

406K

0.00%

ABUS

Arbutus Biopharma Cp

3.16

3.24

3.14

3.22

532K

0.00%

ACRS

Aclaris Therapts

1.25

1.29

1.22

1.26

404K

0.00%

BLUE

Bluebird Bio

4.99

4.98

4.99

217K

0.00%

GALT

Galectin Therapeutic

1.25

1.30

1.25

1.28

179K

0.00%

LXRX

Lexicon Pharmaceuticals, Inc

0.63

0.66

0.62

0.66

0.00%

NCNA

Nucana Plc ADR

0.04

76M

0.00%

PBYI

Puma Biotechnology

3.22

3.26

3.14

3.24

168K

-0.31%

MYGN

Myriad Genetics, Inc

3.86

3.96

3.86

3.91

-0.51%

CYCC

Cyclacel Pharmaceuticals Inc

1.45

1.56

1.36

1.45

146K

-0.68%

OPK

Opko Health Inc

1.26

1.28

1.23

1.26

-0.79%

ADVM

Adverum Biotechnlgs

2.17

2.22

2.10

2.21

213K

-0.90%

IRIX

IRIDEX Corporation

1.00

1.03

0.97

0.98

135K

-1.01%

XERS

Xeris Pharmaceuticals Inc

4.76

4.85

4.73

4.83

-1.02%

HRTX

Heron Therapeutics

1.85

1.86

1.82

1.85

781K

-1.07%

CLSD

Clearside Biomedi

0.86

0.88

0.84

0.86

129K

-1.15%

ESPR

Esperion Theraptc

0.80

0.81

0.76

0.79

-1.25%

CGEN

Compugen Ltd

1.47

1.40

1.45

173K

-1.36%

ASRT

Assertio Therapeutics Inc

0.70

0.69

0.70

138K

-1.41%

GLMD

Galmed Pharmaceutica

1.39

1.35

1.39

102K

-1.42%

NKTR

Nektar Therapeutics

0.63

0.65

0.62

0.65

-1.52%

VRCA

Verrica Pharmaceuticals Inc

0.61

0.64

0.60

0.61

109K

-1.61%

OMER

Omeros Corporation

3.13

3.19

3.05

3.16

570K

-1.86%

RMTI

Rockwell Medical Technologies, Inc

0.99

1.01

0.95

0.98

151K

-2.00%

GERN

Geron Corporation

1.46

1.52

1.42

1.45

12M

-2.03%

VXRT

Vaxart Inc

0.46

0.47

0.45

0.46

767K

-2.13%

PACB

Pacific Biosciences of California

0.92

0.96

0.91

0.92

-2.13%

VYGR

Voyager Therapeut

2.90

2.97

2.87

2.92

304K

-2.34%

ORGO

Organogenesis Holdings Inc

2.93

2.99

2.90

608K

-2.36%

MNKD

MannKind Corporation

4.15

4.19

4.10

4.12

-2.37%

OTLK

Outlook Therapeutics Inc

1.55

1.73

1.47

1.60

-2.44%

LPTX

Leap Therapeutics Inc

0.35

0.38

0.35

0.36

132K

-2.70%

BCLI

Brainstorm Cell

1.08

1.12

1.05

1.08

326K

-2.70%

ALLO

Allogene Therapeutics Inc

1.10

1.12

1.02

1.06

-2.75%

SLDB

Solid Biosciences Inc

2.82

2.73

2.81

872K

-2.77%

CTXR

Citius Pharmaceuticals Inc

0.73

0.75

0.69

0.70

108K

-2.78%

AYTU

Aytu Bioscience Inc

2.01

1.90

1.96

223K

-2.97%

SVRA

Savara Inc

2.87

2.90

2.79

2.84

692K

-3.07%

KOD

Kodiak Sciences Inc

3.36

3.50

3.33

3.44

220K

-3.10%

GLYC

Glycomimetics Inc

0.24

0.25

0.24

124K

-4.00%

SGMO

Sangamo Biosciences, Inc

0.49

0.47

-4.08%

EDIT

Editas Medicine

1.54

1.59

1.51

1.55

950K

-4.32%

ATOS

Atossa Genetics Inc

0.85

0.89

0.83

608K

-4.60%

PHIO

Phio Pharmaceuticals Corp

1.86

1.71

1.75

185K

-4.89%

ALEC

Alector Inc

1.26

1.30

1.22

1.24

955K

-5.34%

SCPH

SC Pharmaceuticals Inc

3.42

3.47

3.30

3.31

283K

-5.70%

APVO

Aptevo Therapeutics Inc

0.29

0.26

0.28

-6.67%

HOOK

Craft Brewers Alliance, Inc

1.62

1.45

1.51

226K

-6.79%

CUE

Cue Biopharma Inc

0.69

0.70

0.65

0.66

307K

-7.04%

IRWD

Ironwood Pharmaceuticals, Inc.

0.61

0.62

0.55

0.57

-8.06%

MRSN

Mersana Therapeutics Inc

0.38

0.39

0.34

0.35

-10.26%

EYEN

Eyenovia Inc

1.91

2.02

1.70

1.77

-12.81%