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Biotech Penny Stocks

Biotech Stocks Under $5 is a list of the top pharmaceutical penny stocks trading on NYSE, NASDAQ, and AMEX. These biotech and pharmaceutical penny stocks are trading under $5 per share and sorted by the biggest gain of the day.


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published on May 23, 2025

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Symbol Company Open High Low Close Volume Percent
TLSA Tiziana Life Sciences Plc ADR 1.44 1.68 1.42 1.58 867K 15.33%
GNPX Genprex Inc 0.27 0.28 0.26 0.28 629K 7.69%
SLS Seligman Lasalle Intl Real Est Fund Inc 1.77 1.93 1.74 1.89 3M 7.39%
ONCY Oncolytics Biotech, Inc 0.40 0.44 0.37 0.42 7M 5.00%
CTMX Cytomx Thera 2.06 2.29 2.03 2.23 3M 4.69%
YMAB Y-Mabs Therapeutics Inc 4.01 4.33 4.00 4.32 234K 4.60%
ADAP Adaptimmune Ther Ads 0.27 0.29 0.26 0.28 386K 3.70%
MBOT Microbot Medical Inc 2.50 2.67 2.47 2.66 1M 3.50%
GOSS Gossamer Bio Inc 1.12 1.21 1.12 1.20 2M 3.45%
PRPH ProPhase Labs Inc 0.30 0.34 0.30 0.32 874K 3.23%
HBIO Harvard Bioscience, Inc 0.32 0.34 0.32 0.34 372K 3.03%
FBIO Fortress Biotech Inc 1.73 1.78 1.69 1.78 145K 2.89%
URGN Urogen Pharma Ltd 3.92 4.23 3.71 4.19 2M 2.70%
AQST Aquestive Therapeutics Inc 2.25 2.38 2.22 2.35 1M 2.62%
ACHV Achieve Life Sciences Inc 2.90 3.05 2.89 3.04 112K 2.36%
STRO Sutro Biopharma Inc 0.87 0.92 0.85 0.92 721K 2.22%
VNDA Vanda Pharmaceuticals Inc 4.20 4.33 4.17 4.33 297K 2.12%
VERU Veru Inc 0.49 0.50 0.48 0.50 948K 2.04%
IOVA Iovance Biotherapeutics Inc 1.70 1.79 1.67 1.78 8M 1.71%
IFRX Fireman B.V. 1.78 1.90 1.75 1.85 212K 1.65%
BTAI Bioxcel Therapeutics Inc 1.36 1.42 1.30 1.39 105K 1.46%
AKBA Akebia Therapeutics 2.81 2.87 2.76 2.86 3M 1.06%
MBRX Metabasis Therapeutics, Inc 0.94 0.96 0.92 0.95 104K 1.06%
AGEN Antigenics, Inc 3.70 3.84 3.59 3.82 423K 0.79%
AUTL Autolus Therapeutics Plc ADR 1.53 1.54 1.49 1.54 1M 0.65%
CRVS Corvus Pharma Com 3.46 3.51 3.38 3.49 465K 0.58%
CKPT Checkpoint Therapeutics Inc 4.17 4.19 4.16 4.19 2M 0.48%
QTRX Quanterix Corp 4.64 4.89 4.60 4.85 410K 0.41%
ARDX Ardelyx Inc 3.86 4.00 3.86 3.97 3M 0.25%
AEMD Aethlon Medical 0.39 0.40 0.38 0.40 160K 0.00%
CLRB Cellectar Biosc 0.25 0.26 0.24 0.25 345K 0.00%
ITRM Iterum Therapeutics Plc 0.92 0.94 0.91 0.93 375K 0.00%
OVID Ovid Therapeutics Inc 0.29 0.29 0.28 0.29 519K 0.00%
FGEN Fibrogen Inc CS 0.34 0.34 0.32 0.33 406K 0.00%
ABUS Arbutus Biopharma Cp 3.16 3.24 3.14 3.22 532K 0.00%
ACRS Aclaris Therapts 1.25 1.29 1.22 1.26 404K 0.00%
BLUE Bluebird Bio 4.99 4.99 4.98 4.99 217K 0.00%
GALT Galectin Therapeutic 1.25 1.30 1.25 1.28 179K 0.00%
LXRX Lexicon Pharmaceuticals, Inc 0.63 0.66 0.62 0.66 3M 0.00%
NCNA Nucana Plc ADR 0.04 0.04 0.04 0.04 76M 0.00%
PBYI Puma Biotechnology 3.22 3.26 3.14 3.24 168K -0.31%
MYGN Myriad Genetics, Inc 3.86 3.96 3.86 3.91 2M -0.51%
CYCC Cyclacel Pharmaceuticals Inc 1.45 1.56 1.36 1.45 146K -0.68%
OPK Opko Health Inc 1.26 1.28 1.23 1.26 2M -0.79%
ADVM Adverum Biotechnlgs 2.17 2.22 2.10 2.21 213K -0.90%
IRIX IRIDEX Corporation 1.00 1.03 0.97 0.98 135K -1.01%
XERS Xeris Pharmaceuticals Inc 4.76 4.85 4.73 4.83 1M -1.02%
HRTX Heron Therapeutics 1.85 1.86 1.82 1.85 781K -1.07%
CLSD Clearside Biomedi 0.86 0.88 0.84 0.86 129K -1.15%
ESPR Esperion Theraptc 0.80 0.81 0.76 0.79 7M -1.25%
CGEN Compugen Ltd 1.47 1.47 1.40 1.45 173K -1.36%
ASRT Assertio Therapeutics Inc 0.70 0.70 0.69 0.70 138K -1.41%
GLMD Galmed Pharmaceutica 1.39 1.39 1.35 1.39 102K -1.42%
NKTR Nektar Therapeutics 0.63 0.65 0.62 0.65 1M -1.52%
VRCA Verrica Pharmaceuticals Inc 0.61 0.64 0.60 0.61 109K -1.61%
OMER Omeros Corporation 3.13 3.19 3.05 3.16 570K -1.86%
RMTI Rockwell Medical Technologies, Inc 0.99 1.01 0.95 0.98 151K -2.00%
GERN Geron Corporation 1.46 1.52 1.42 1.45 12M -2.03%
VXRT Vaxart Inc 0.46 0.47 0.45 0.46 767K -2.13%
PACB Pacific Biosciences of California 0.92 0.96 0.91 0.92 7M -2.13%
VYGR Voyager Therapeut 2.90 2.97 2.87 2.92 304K -2.34%
ORGO Organogenesis Holdings Inc 2.93 2.99 2.90 2.90 608K -2.36%
MNKD MannKind Corporation 4.15 4.19 4.10 4.12 2M -2.37%
OTLK Outlook Therapeutics Inc 1.55 1.73 1.47 1.60 2M -2.44%
LPTX Leap Therapeutics Inc 0.35 0.38 0.35 0.36 132K -2.70%
BCLI Brainstorm Cell 1.08 1.12 1.05 1.08 326K -2.70%
ALLO Allogene Therapeutics Inc 1.10 1.12 1.02 1.06 3M -2.75%
SLDB Solid Biosciences Inc 2.82 2.82 2.73 2.81 872K -2.77%
CTXR Citius Pharmaceuticals Inc 0.73 0.75 0.69 0.70 108K -2.78%
AYTU Aytu Bioscience Inc 2.01 2.01 1.90 1.96 223K -2.97%
SVRA Savara Inc 2.87 2.90 2.79 2.84 692K -3.07%
KOD Kodiak Sciences Inc 3.36 3.50 3.33 3.44 220K -3.10%
GLYC Glycomimetics Inc 0.24 0.25 0.24 0.24 124K -4.00%
SGMO Sangamo Biosciences, Inc 0.49 0.49 0.47 0.47 3M -4.08%
EDIT Editas Medicine 1.54 1.59 1.51 1.55 950K -4.32%
ATOS Atossa Genetics Inc 0.85 0.89 0.83 0.83 608K -4.60%
PHIO Phio Pharmaceuticals Corp 1.86 1.86 1.71 1.75 185K -4.89%
ALEC Alector Inc 1.26 1.30 1.22 1.24 955K -5.34%
SCPH SC Pharmaceuticals Inc 3.42 3.47 3.30 3.31 283K -5.70%
APVO Aptevo Therapeutics Inc 0.29 0.29 0.26 0.28 2M -6.67%
HOOK Craft Brewers Alliance, Inc 1.62 1.62 1.45 1.51 226K -6.79%
CUE Cue Biopharma Inc 0.69 0.70 0.65 0.66 307K -7.04%
IRWD Ironwood Pharmaceuticals, Inc. 0.61 0.62 0.55 0.57 5M -8.06%
MRSN Mersana Therapeutics Inc 0.38 0.39 0.34 0.35 3M -10.26%
EYEN Eyenovia Inc 1.91 2.02 1.70 1.77 1M -12.81%



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