Biotech Stocks Under $5 - Hot Biotech Penny Stocks

Biotech Penny Stocks

Biotech Stocks Under $5 is a list of the top pharmaceutical penny stocks trading on NYSE, NASDAQ, and AMEX. These biotech and pharmaceutical penny stocks are trading under $5 per share and sorted by the biggest gain of the day.

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Updated on May 13, 2026

Symbol

Open

High

Low

Volume

Percent

Company

VIVO

3.2

4.47

3.14

4.23

34.29%

Meridian Bioscience, Inc

SNGX

0.31

0.37

0.3

0.36

12.50%

Soligenix Inc

ORGO

2.4

2.71

2.37

2.71

974K

12.45%

Organogenesis Holdings Inc

DARE

2.77

2.84

2.52

2.83

429K

8.43%

Dare Bioscience Inc

AUTL

1.7

1.75

1.57

1.72

6.83%

Autolus Therapeutics Plc ADR

VTGN

0.64

0.66

0.6

0.66

828K

6.45%

Vistagen Therap. Com

PRQR

1.6

1.72

1.58

1.71

574K

6.21%

Proqr Therapeutics

HSDT

2.09

2.27

2.05

2.22

274K

5.71%

Helius Medical Technologies Inc

CTXR

0.63

0.67

0.6

0.66

659K

4.76%

Citius Pharmaceuticals Inc

PHIO

1.1

1.15

1.1

1.15

114K

3.60%

Phio Pharmaceuticals Corp

IFRX

2.26

2.69

2.26

2.53

3.27%

Fireman B.V.

GOSS

0.34

0.36

0.33

0.35

2.94%

Gossamer Bio Inc

ACIU

2.86

2.72

2.84

203K

2.53%

AC Immune S.A.

IOVA

3.6

3.71

3.5

3.66

2.52%

Iovance Biotherapeutics Inc

ORMP

4.52

4.63

4.45

4.55

152K

2.25%

Oramed Pharma

2.3

2.38

2.15

2.32

284K

1.75%

Embarq Corporation

VSTM

4.69

4.91

4.49

4.71

1.73%

Verastem Inc

LXRX

2.43

2.51

2.34

2.44

1.67%

Lexicon Pharmaceuticals, Inc

AVXL

3.1

3.11

3.01

3.1

694K

1.64%

Anavex Lf SC

HOTH

0.65

0.67

0.64

0.66

106K

1.54%

Hoth Therapeutics Inc

GNPX

0.84

0.87

0.82

0.85

160K

1.19%

Genprex Inc

ALLO

2.3

2.37

2.22

2.33

0.87%

Allogene Therapeutics Inc

AGEN

3.45

3.58

3.39

3.47

474K

0.87%

Antigenics, Inc

GERN

1.42

1.45

1.4

1.42

22M

0.71%

Geron Corporation

Symbol

Open

High

Low

Volume

Percent

Company

VYGR

4.29

4.43

4.1

4.16

332K

0.24%

Voyager Therapeut

AKBA

1.15

1.2

1.15

1.19

0.00%

Akebia Therapeutics

OPK

1.12

1.1

1.11

0.00%

Opko Health Inc

SGMO

0.15

0.13

0.14

0.00%

Sangamo Biosciences, Inc

ABUS

4.3

4.67

4.27

4.32

992K

-0.23%

Arbutus Biopharma Cp

ESPR

3.1

3.14

3.1

3.13

-0.32%

Esperion Theraptc

CHRS

1.71

1.79

1.6

1.7

-0.58%

Charming Shoppes, Inc

ALDX

1.77

1.65

1.7

-0.58%

Aldeyra Therapeu

PACB

1.3

1.33

1.25

1.28

-0.78%

Pacific Biosciences of California

BTAI

1.21

1.17

1.19

310K

-0.83%

Bioxcel Therapeutics Inc

MGNX

3.29

3.6

3.24

3.48

-0.85%

Macrogenics

GALT

2.19

2.33

2.19

2.24

355K

-0.88%

Galectin Therapeutic

MBOT

2.19

2.22

2.14

2.17

-0.91%

Microbot Medical Inc

ALEC

2.13

2.21

2.09

2.15

285K

-0.92%

Alector Inc

AQST

4.34

4.37

4.1

4.13

-1.20%

Aquestive Therapeutics Inc

SCYX

0.78

0.73

0.76

353K

-1.30%

Scynexis Inc

FBIO

2.22

2.3

2.19

2.24

307K

-1.32%

Fortress Biotech Inc

EDIT

2.91

3.19

2.86

2.9

684K

-1.36%

Editas Medicine

QTRX

2.82

2.99

2.81

2.88

-1.37%

Quanterix Corp

RCKT

3.55

3.65

3.54

3.59

-1.37%

Rocket Pharmaceuticals Inc

BNGO

1.26

1.33

1.24

1.25

294K

-1.57%

Bionano Genomics Inc

IMMP

0.45

0.47

0.45

0.46

559K

-2.13%

Immutep Ltd ADR

MNKD

3.3

3.34

3.11

3.21

-2.13%

MannKind Corporation

ALT

3.12

3.19

2.89

3.01

-2.27%

iShares Diversified Alternatives Trust

CTMX

3.84

3.94

3.71

3.79

-2.32%

Cytomx Thera

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Symbol

Open

High

Low

Volume

Percent

Company

CLRB

2.92

2.87

2.92

150K

-2.34%

Cellectar Biosc

OVID

2.9

2.95

2.73

2.8

-2.44%

Ovid Therapeutics Inc

SIGA

4.45

4.47

4.3

4.31

361K

-3.15%

SIGA Technologies, Inc

TLSA

1.55

1.46

1.51

268K

-3.21%

Tiziana Life Sciences Plc ADR

ONCY

0.9

0.92

0.87

501K

-3.33%

Oncolytics Biotech, Inc

SPRO

2.48

2.59

2.43

2.44

575K

-3.94%

SmartPros Ltd.

HRTX

0.94

0.98

0.92

-4.17%

Heron Therapeutics

OTLK

0.24

0.25

0.23

-4.17%

Outlook Therapeutics Inc

CNTX

2.48

2.35

2.37

337K

-4.82%

Context Therapeutics Inc

FATE

2.24

2.27

1.83

2.13

-5.33%

Fate Therapeutics

RMTI

0.84

0.79

159K

-5.95%

Rockwell Medical Technologies, Inc

MYGN

4.1

3.73

3.74

-8.33%

Myriad Genetics, Inc

MBRX

2.43

2.61

2.13

958K

-8.97%

Metabasis Therapeutics, Inc

CRIS

0.52

0.57

0.49

0.5

576K

-9.09%

Curis, Inc

ASNS

0.09

0.1

0.08

0.09

376K

-10.00%

Actelis Networks Inc

IRWD

4.21

3.57

3.66

-10.51%

Ironwood Pharmaceuticals, Inc.