Biotech Penny Stocks
Biotech Penny Stocks is a complete list of biotech stocks under $1 trading on NYSE, NASDAQ, AMEX, and OTCBB. The biotechnology and pharmaceutical penny stocks list is sorted by the biggest gain of the day.

published on June 13, 2025
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Symbol |
Company |
Open |
High |
Low |
Close |
Volume |
Percent |
VXRT |
Vaxart Inc |
0.52 |
0.78 |
0.49 |
0.70 |
29M |
29.63% |
CYCC |
Cyclacel Pharmaceuticals Inc |
0.35 |
0.46 |
0.32 |
0.41 |
7M |
13.89% |
TLSA |
Tiziana Life Sciences Plc ADR |
1.52 |
1.64 |
1.47 |
1.55 |
1M |
9.15% |
ONCY |
Oncolytics Biotech, Inc |
0.58 |
0.61 |
0.54 |
0.61 |
756K |
5.17% |
CASI |
Casi Phrmactcls Inc |
1.75 |
2.92 |
1.72 |
1.84 |
4M |
2.79% |
MRSN |
Mersana Therapeutics Inc |
0.36 |
0.38 |
0.35 |
0.37 |
1M |
2.78% |
GALT |
Galectin Therapeutic |
1.35 |
1.38 |
1.33 |
1.37 |
188K |
2.24% |
PACB |
Pacific Biosciences of California |
1.15 |
1.22 |
1.13 |
1.20 |
7M |
1.69% |
ASRT |
Assertio Therapeutics Inc |
0.61 |
0.65 |
0.61 |
0.63 |
228K |
1.61% |
SLS |
Seligman Lasalle Intl Real Est Fund Inc |
1.65 |
1.73 |
1.63 |
1.66 |
3M |
0.61% |
AYTU |
Aytu Bioscience Inc |
1.93 |
1.97 |
1.91 |
1.95 |
94K |
0.00% |
IRIX |
IRIDEX Corporation |
0.96 |
0.98 |
0.94 |
0.94 |
186K |
0.00% |
HOOK |
Craft Brewers Alliance, Inc |
1.42 |
1.44 |
1.40 |
1.42 |
55K |
0.00% |
GLMD |
Galmed Pharmaceutica |
1.61 |
1.65 |
1.53 |
1.60 |
300K |
-0.62% |
OPK |
Opko Health Inc |
1.32 |
1.36 |
1.32 |
1.33 |
2M |
-0.75% |
ITRM |
Iterum Therapeutics Plc |
0.98 |
1.02 |
0.97 |
0.99 |
459K |
-1.00% |
OTLK |
Outlook Therapeutics Inc |
1.80 |
1.85 |
1.78 |
1.82 |
303K |
-1.09% |
CGEN |
Compugen Ltd |
1.65 |
1.69 |
1.61 |
1.64 |
174K |
-1.20% |
SCYX |
Scynexis Inc |
0.82 |
0.83 |
0.80 |
0.81 |
99K |
-1.22% |
STRO |
Sutro Biopharma Inc |
0.82 |
0.82 |
0.76 |
0.80 |
700K |
-1.23% |
CLSD |
Clearside Biomedi |
0.79 |
0.82 |
0.78 |
0.80 |
187K |
-1.23% |
HBIO |
Harvard Bioscience, Inc |
0.51 |
0.53 |
0.50 |
0.51 |
653K |
-1.92% |
MGNX |
Macrogenics |
1.50 |
1.60 |
1.48 |
1.52 |
952K |
-1.94% |
SGMO |
Sangamo Biosciences, Inc |
0.49 |
0.51 |
0.47 |
0.49 |
3M |
-2.00% |
GOSS |
Gossamer Bio Inc |
1.27 |
1.29 |
1.20 |
1.24 |
1M |
-2.36% |
LPTX |
Leap Therapeutics Inc |
0.41 |
0.44 |
0.40 |
0.41 |
162K |
-2.38% |
IFRX |
Fireman B.V. |
0.80 |
0.80 |
0.76 |
0.78 |
819K |
-2.50% |
ESPR |
Esperion Theraptc |
1.18 |
1.22 |
1.16 |
1.17 |
2M |
-2.50% |
CLLS |
Cellectis S.A. ADR |
1.39 |
1.43 |
1.33 |
1.33 |
64K |
-2.92% |
PRPH |
ProPhase Labs Inc |
0.33 |
0.36 |
0.33 |
0.33 |
515K |
-2.94% |
CNTX |
Context Therapeutics Inc |
0.63 |
0.64 |
0.61 |
0.63 |
171K |
-3.08% |
PRQR |
Proqr Therapeutics |
1.95 |
1.95 |
1.88 |
1.88 |
307K |
-3.09% |
RMTI |
Rockwell Medical Technologies, Inc |
0.97 |
0.97 |
0.94 |
0.94 |
225K |
-3.09% |
DRRX |
DURECT Corporation |
0.62 |
0.66 |
0.59 |
0.62 |
62K |
-3.13% |
GERN |
Geron Corporation |
1.53 |
1.57 |
1.50 |
1.51 |
7M |
-3.21% |
OVID |
Ovid Therapeutics Inc |
0.29 |
0.30 |
0.27 |
0.28 |
1M |
-3.45% |
ATOS |
Atossa Genetics Inc |
0.85 |
0.85 |
0.81 |
0.83 |
515K |
-3.49% |
BOLD |
Boundless Bio Inc. |
1.07 |
1.12 |
1.04 |
1.05 |
122K |
-3.67% |
CHRS |
Charming Shoppes, Inc |
0.78 |
0.78 |
0.76 |
0.76 |
1M |
-3.80% |
ACRS |
Aclaris Therapts |
1.50 |
1.55 |
1.47 |
1.47 |
468K |
-3.92% |
HRTX |
Heron Therapeutics |
1.97 |
2.00 |
1.92 |
1.93 |
748K |
-3.98% |
ADAP |
Adaptimmune Ther Ads |
0.25 |
0.26 |
0.24 |
0.24 |
565K |
-4.00% |
LXRX |
Lexicon Pharmaceuticals, Inc |
0.68 |
0.71 |
0.67 |
0.67 |
3M |
-4.29% |
ALLO |
Allogene Therapeutics Inc |
1.35 |
1.42 |
1.33 |
1.34 |
2M |
-4.29% |
MBRX |
Metabasis Therapeutics, Inc |
0.65 |
0.67 |
0.63 |
0.64 |
306K |
-4.48% |
ALEC |
Alector Inc |
1.57 |
1.59 |
1.47 |
1.54 |
409K |
-4.94% |
MRKR |
Marker Therapeutics Inc |
1.67 |
1.73 |
1.55 |
1.60 |
170K |
-5.33% |
CTXR |
Citius Pharmaceuticals Inc |
0.91 |
0.92 |
0.86 |
0.87 |
624K |
-5.43% |
FBIO |
Fortress Biotech Inc |
1.92 |
1.94 |
1.85 |
1.85 |
243K |
-5.61% |
ACIU |
AC Immune S.A. |
2.05 |
2.05 |
1.91 |
1.95 |
134K |
-5.80% |
GLYC |
Glycomimetics Inc |
0.17 |
0.17 |
0.15 |
0.16 |
1M |
-5.88% |
VERU |
Veru Inc |
0.64 |
0.65 |
0.61 |
0.61 |
2M |
-6.15% |
CUE |
Cue Biopharma Inc |
0.64 |
0.66 |
0.59 |
0.60 |
97K |
-6.25% |
GNPX |
Genprex Inc |
0.31 |
0.31 |
0.29 |
0.29 |
745K |
-6.45% |
XTLB |
Xtl Biopharma Ads |
1.23 |
1.39 |
1.05 |
1.12 |
66K |
-6.67% |
BCLI |
Brainstorm Cell |
1.16 |
1.18 |
1.08 |
1.10 |
258K |
-6.78% |
CLRB |
Cellectar Biosc |
0.42 |
0.45 |
0.41 |
0.41 |
3M |
-6.82% |
UBX |
Unity Biotechnology Inc |
0.83 |
0.86 |
0.80 |
0.80 |
167K |
-6.98% |
VRCA |
Verrica Pharmaceuticals Inc |
0.64 |
0.68 |
0.62 |
0.62 |
129K |
-7.46% |
IRWD |
Ironwood Pharmaceuticals, Inc. |
0.64 |
0.65 |
0.61 |
0.62 |
2M |
-7.46% |
MBIO |
Mustang Bio Inc |
1.27 |
1.27 |
1.16 |
1.17 |
92K |
-7.87% |
HOTH |
Hoth Therapeutics Inc |
1.36 |
1.38 |
1.27 |
1.30 |
715K |
-8.45% |
FATE |
Fate Therapeutics |
1.40 |
1.40 |
1.27 |
1.28 |
2M |
-8.57% |
EDIT |
Editas Medicine |
2.02 |
2.12 |
1.94 |
1.97 |
3M |
-9.63% |
EQ |
Embarq Corporation |
0.36 |
0.36 |
0.33 |
0.35 |
1M |
-10.26% |
AEMD |
Aethlon Medical |
1.92 |
2.00 |
1.75 |
1.76 |
66K |
-10.66% |
ENTX |
Entera Bio Ltd |
2.01 |
2.07 |
1.84 |
1.86 |
52K |
-11.00% |
BTAI |
Bioxcel Therapeutics Inc |
1.70 |
1.70 |
1.53 |
1.56 |
191K |
-11.86% |
HSDT |
Helius Medical Technologies Inc |
0.54 |
0.55 |
0.48 |
0.51 |
9M |
-15.00% |
FGEN |
Fibrogen Inc CS |
0.29 |
0.29 |
0.24 |
0.26 |
4M |
-16.13% |
ADIL |
Adial Pharmaceuticals Inc |
0.44 |
0.44 |
0.35 |
0.35 |
2M |
-22.22% |
NCNA |
Nucana Plc ADR |
0.13 |
0.14 |
0.11 |
0.11 |
116M |
-26.67% |

Biotech Stocks Under $1
Biotech stocks have a volatile year because of the coronavirus pandemic. Traders bet on some of the biotech stocks hoping for a Covid-19 vaccine from these biotech companies. Many of the biotech stocks under $1 seeing roller coaster rides with their stock prices.
Buying biotech stocks is more like gambling than investing. Many biotech stocks rely on positive news to make big moves only to see their stock prices fading when the news is over.
Top 10 Biotech Penny Stocks to Watch
Following are the top 10 biotech penny stocks to watch today, these are the biotech penny stocks that made big moves.
- Vaxart Inc (NASDAQ:VXRT)
- Cyclacel Pharmaceuticals Inc (NASDAQ:CYCC)
- Tiziana Life Sciences Plc ADR (NASDAQ:TLSA)
- Oncolytics Biotech, Inc (NASDAQ:ONCY)
- Casi Phrmactcls Inc (NASDAQ:CASI)
- Mersana Therapeutics Inc (NASDAQ:MRSN)
- Galectin Therapeutic (NASDAQ:GALT)
- Pacific Biosciences of California (NASDAQ:PACB)
- Assertio Therapeutics Inc (NASDAQ:ASRT)
- Seligman Lasalle Intl Real Est Fund Inc (NASDAQ:SLS)
How to Trade Biotech Penny Stocks
In fact, biotech penny stocks can be traded just like penny stocks from any other industry or sector. Read this penny stock guide on how to swing trade biotech stocks under $1.
One thing to remember, though, is never to hold a biotech penny stock for the long term.
Pharmaceutical Penny Stocks
The list above is mostly biotech penny stocks with some pharma penny stocks. The differences between biotech stocks and pharmaceutical are the medicine made by biotech companies are derived from living organisms whereas the medicine made by pharmaceutical companies usually have a chemical basis.
OTC Biotech Stocks Under $1
Following is a list of biotech stocks under $1 that are listed on the OTC market or as pink sheet stock.
Updated on June 13, 2025
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